Premature adrenarche (PA) was previously regarded as a benign variant of normal sexual development, but recent studies have connected it with risk of developing ovarian hyperandrogenism and metabolic ...

Expert Rev Endocrinol Metab. 2012;7(5):555-566. Division of Endocrinology, Department of Clinical Medicine, University Alma Mater Studiorum, St. Orsola-Malpighi Hospital, Via Massarenti 9, 40138, ...

Agents that directly lower ACTH secretion by a pituitary adenoma represent an attractive option for the treatment of Cushing's disease, as these drugs directly target the pathogenesis of disease.

This glucocorticoid is a steroid hormone that is created from cholesterol and is released from the adrenal cortex within the zona fasciculata layer. The hypothalamus-pituitary-adrenal (HPA) axis works ...