A high-yield, one-pot, scalable reaction facilitates the production of biologically relevant amide compounds using less reactive nitrogen-containing heterocyclic compounds and carboxylic acid without ...
Medicines come from chemical reactions, and better chemical reactions lead to better medicines. Yet, the most popular reaction used in drug discovery, called the amide coupling, makes an inherently ...
Commercial-scale amide formation and an improved process route for a tetracycline derivative are some recent developments in API synthesis. Process chemists in the fine-chemicals and pharmaceutical ...
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