New research reveals how a class of neurons that help coordinate communication in the brain link up with their target cells, ...

Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.

Different populations of cells in the mouse brain, each one targeted with high specificity by one of the many new genetic tools developed at the Allen Institute. The brain is like an ...

Using advanced single-nuclei RNA sequencing (snRNA-seq) and a widely used preclinical model for Alzheimer's disease, researchers from Mass General Brigham and collaborators at SUNY Upstate Medical ...

Alzheimer’s disease has long looked like a slow-motion wildfire, starting in one part of the brain and then advancing along ...

Researchers at McGill University and the Douglas Institute have identified two specific types of brain cells that are altered in people with depression. The study, published in Nature Genetics, opens ...

Researchers have shown in mice that brain cells known as astrocytes are required for a signaling chemical called norepinephrine to modify brain activity, changing the textbook understanding that ...

Brain endothelial cells (BEC) targeted by a BEC-enhancer AAV vector tool, developed by the Xu Lab and the Center for Neural Circuit Mapping team. Viral labeling (green) overlaps with endothelial cells ...

Explore the groundbreaking role of the OTULIN enzyme in regulating the immune system and its link to neurodegenerative ...