According to an international multicenter study, CD2-negative mast cells are associated with significantly reduced overall survival in patients with SM. Patients with CD2-negative mast cells have ...
T cell activation through the CD2 cell surface receptor is transmitted by proline-rich sequences within its cytoplasmic tail. A membrane-proximal proline-rich tandem repeat, involved in cytokine ...
Figure 1: The crystal structure of the wild type metastable intertwined dimer (Cα trace, one polypeptide chain green, other chain in red) shows a buried, enclosed hydrophilic interface (center) which ...
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