A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...

"Vaccine strategies have focused on inducing inflammatory CD4 T cells, but it might be time to shift our focus to reducing inflammation to the minimum level needed to limit growth of the bacteria, ...

These immune CD8 T cells may provide a target for treating the buildup of fatty lesions in the arteries called atherosclerosis. Atherosclerosis is the underlying pathology of heart attacks and strokes ...

The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...

Interleukin-2 (IL-2) is a cytokine, a type of immune system signaling molecule, that plays a crucial role in the body's response to microbial infections and in distinguishing between self and non-self ...

The study evaluated GEO-CM04S1 in the K18-hACE2 lethal mouse model, comparing immune responses and efficacy to experimental MVA-vectored vaccine constructs expressing spike alone (S) or nucleocapsid ...

How do tertiary lymphoid structures influence immunotherapy outcomes in Merkel cell carcinoma? Spatial proteomics reveals key ...