Members of the CD44 transmembrane protein family have functions in many processes in normal life (for example, in haematopoiesis, the immune system and organogenesis), and in pathological situations ...

Figure 2: Donor CD44 is not required for engraftment of B-ALL–initiating cells. Figure 4: CD44-specific antibody treatment prolongs survival of recipients of BCR-ABL1–transduced progenitors. We ...

Elevated salivary levels of CD44 and total protein (TP) can identify head and neck cancer patients with an increased risk for cancer recurrence, according to a study published online Aug. 15 in JAMA ...

A research team affiliated with UNIST has made a significant discovery explaining why liver cancers associated with obesity ...

Does knowledge guide practice? Another look at the management of non-small-cell lung cancer. CD44 is a hyaluronic acid receptor that exists as a standard 90-kd form (CD44S) as well as several CD44 ...

Uniform approach to risk classification and treatment assignment for children with acute lymphoblastic leukemia. Adjuvant cyclophosphamide, methotrexate, and fluorouracil versus fluorouracil, ...

Abstract Endotrophin (ETP) is a cleavage fragment of collagen VI α3 (COL6A3) that functions as a potent fibrotic and pro-tumorigenic factor. ETP is a ...

Researchers investigating the role of the protein CD44 in obesity and metabolic health found that CD44-deficient mice stayed lean even on a high-fat diet, while the control mice developed obesity. A ...

Scientists in China have found a new potential drug target for weight loss. Blocking a protein called CD44 has been shown to protect against obesity in mice on a high-fat diet, specifically by ...

Breast cancers contain a minority population of cancer cells characterized by CD44 expression but low or undetectable levels of CD24 (CD44+CD24−/low) that have higher tumorigenic capacity than other ...

Surprising findings from a study in The American Journal of Pathology show that mice with a CD44 protein deficiency stay lean, despite being on a high-fat diet Researchers investigating the role of ...

In a major scientific breakthrough, researchers from Monash University and the Lions Eye Institute have discovered a tissue protein that acts as a central ‘traffic controller’ for immune cells and can ...