Calcium signalling represents a fundamental process in cellular communication, orchestrating diverse physiological responses from muscle contraction to neurotransmission and gene regulation. At the ...

Recent studies settle a debate over how the second messenger NAADP, with no known binding site, evokes calcium release from ion channels. Adding to the excitement in the field, another paper published ...

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ...

A faulty ion channel function is a consistent biological feature of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome ...

BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating ...

Mitochondrial calcium signalling plays a fundamental role in cellular homeostasis by modulating energy production and activating key metabolic enzymes. Calcium ions (Ca2+) are dynamically exchanged ...

An article published in The Faseb Journal describes a Brazilian study analyzing the correlation between two key energy metabolism regulation processes: the absorption and release of calcium ions by ...

HHMI researchers have discovered that a specific type of calcium channel—a pore-like protein that is nestled in the cell membrane and controls the flow of calcium into the cell—regulates the ...

Healthy digestion depends on a delicate balance of fluid in the gut. At the heart of that balance are epithelial cells, which line the intestinal wall and control how salt and water move in and out of ...