BV100 Phase 1, single- and multiple-ascending dose clinical trial data include pharmacokinetics, safety and tolerability data. BV100 demonstrated a dose-proportional pharmacokinetic profile and was ...

Antimicrobial resistance has become one of the greatest threats to public health, with rising resistance to carbapenems being a particular concern due to the lack of effective and safe alternative ...

Under a microscope, this drug-resistant superbug looks as benign as a handful of pebbles. Yet carbapenem-resistant Acinetobacter baumannii, or CRAB, is a nightmare for hospitals worldwide, as it kills ...

The clinical burden of carbapenem-resistant Acinetobacter baumannii has worsened across U.S. hospitals in recent years, according to a study published April 17 in BMC Infectious Diseases. The ...

Please provide your email address to receive an email when new articles are posted on . “What antibiotic should I use to treat this patient’s Klebsiella pneumoniae? It’s resistant to carbapenems, and ...

The carbapenem antibiotics (imipenem, meropenem and doripenem) are considered the agents of choice for A. baumannii infections. The presence of resistance to these agents constrains therapeutic ...

Broad spectrum carbapenems were the most commonly used therapy for targeted treatment of extended-spectrum cephalosporin-resistant (ECR) Enterobacterales infections in U.S. hospitals, according to a ...

Share on Pinterest The CDC issued a warning over a multi-drug-resistant “nightmare bacteria” that’s been surging in the United States. Getty Images A new CDC report found a sharp increase in ...

Carbapenem-resistant Enterobacteriaceae (CRE) refers to Enterobacteriaceae bacteria that are resistant to strong antibiotics known as Carbapenems. Enterobacteriaceae are bacteria that live in a ...

CORRECTED September 30, 2025 // An earlier version of this article incorrectly stated the two drugs which are effective against NDM-CRE. The article has been updated to state aztreonam-avibactam and ...