Centrioles and basal bodies (hereafter referred to as 'centrioles' for simplicity) are essential for the formation of cilia, flagella and centrosomes. Therefore, understanding the mechanisms governing ...

EPFL scientists discover that certain cell structures, the centrioles, could act as information carriers throughout cell generations. The discovery raises the possibility that transmission of ...

All life on earth depends upon the process of mitosis or cell division in which the chromosomal content of a cell is equally divided between two new cells. For mitosis to occur, the chromosomes in ...

Cells contain various specialized structures—such as the nucleus, mitochondria or peroxisomes—known as "organelles." Tracing their genesis and determining their structure is fundamental to ...

Planar cell polarity (PCP) signalling is a well-conserved developmental pathway regulating cellular orientation during development. An evolutionarily conserved pathway readout is not established and, ...

Centrioles, the barrel-shaped organelles best known for their role in cell division, may also put their stamp on early embryos. In a newly fertilized embryo, the centrioles that are present come ...

How cell division occurs and is coordinated with organismal development is subject of intense research interest, as is how this process malfunctions in the development of tumors. Researchers have been ...

In a study published in ACS Nano, researchers from National Taiwan University report a new expansion microscopy strategy termed high-fold homogeneous expansion microscopy (hiHomoExM), capable of ...

A two-step recruitment model based on the findings for the CEP57-CEP63-CEP152 complex during a single cell cycle. (A) During S to G2 phase, CEP57 is gradually recruited to the procentriole, crucial ...

Mitosis is the process by which the genetic information encoded on chromosomes is equally distributed to two daughter cells, a fundamental feature of all life on earth. Scientists now examine how ...

Life doesn't begin the way we thought it did. A new study at The University of Toledo shows that a father donates not one, but two centrioles through the sperm during fertilization, and the newly ...