Scientists at Fox Chase Cancer Center have discovered a unique method of attack that may be used to inhibit signaling enzymes called kinases, which often have a role in sustaining drug-resistant ...

The development of new therapeutics targeting protein kinases is crucial in the fight against diseases like cancer.

HISTOCHEMICAL reactions are dependent on enzyme specificity. The reaction should be enhanced by conditions that are optimal for the enzyme and should be diminished in the presence of inhibitors.

AI‑driven protein design creates potent anti‑CRISPR inhibitors that block Cas13 activity, offering a new potential tool for safer, more controlled gene editing.

Enzyme inhibitors play a pivotal role in pharmaceutical and nutraceutical industries. The primary understanding of the action of inhibitors helps pharmacologists during the design process for ...

DelveInsight's DUB Inhibitors Market Size, Target Population, Competitive Landscape & Market Forecast report includes a ...

Together with researchers from University Hospital Mainz, the University of Regensburg and the IRCM in Montreal (Canada), a research team from Friedrich Schiller University Jena has discovered a novel ...

Among patients with idiopathic pulmonary fibrosis, the risk for all-cause mortality was significantly lower with vs. without angiotensin-converting enzyme inhibitor use started within 5 years before ...

Background: Perchlorate (ClO₄⁻) is an environmental contaminant known to disrupt the thyroid axis of many terrestrial and aquatic species. ClO₄⁻ competitively inhibits iodide uptake into the thyroid ...