In a recent study published in Nature Immunology, researchers investigated the direct influence of sodium (Na+) ions on the cytotoxic cluster of differentiation 8 (CD8)-expressing T cells and hence on ...

CD8 + cytotoxic T lymphocytes (CTLs) serve as central effectors in cancer immunotherapy by directly eliminating tumor cells. However, current clinical therapies face significant limitations. These ...

New findings reveal how cancer manipulates immune pathways and highlight therapeutic strategies to unleash T-cells against even the most resistant tumors. Study: Cancer cells impair monocyte-mediated ...

Cytotoxic T cells are star players in the adaptive immune system, enforcing protection against invading viruses or cancer cells. However, evidence has been mounting that the cells may also deal a ...

Researchers found a way to boost aging immune systems by turning the liver into a temporary source of immune support signals ...

A joint research team of the Korea Advanced Institute of Science and Technology (KAIST) and domestic biotechnology firm ...

Scientists are supercharging T cells with multipotent stromal cells’ mitochondria to make them more ferocious invaders of the tumor microenvironment. An international collaboration between researchers ...

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy by harnessing the body's immune system to target ...

Balancing the immune system is a delicate act. If it’s too weak, infections and cancer can take hold; if it’s too strong, autoimmune diseases or transplant rejection can occur. Researchers have ...

Meet the Jekyll and Hyde of the immune system: activated CD8⁺ T cells. On June 24 in Nature Immunology, researchers led by Dorian McGavern at the National Institutes of Health introduce a granzyme ...