Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. UCLA researchers, using an experiment that elucidated the function of tens of thousands of ...

Study highlights importance of cancer driver biology in translating results from lab to patients -- -- Findings validate proprietary OncoSLX Platform (TM), a pharmacogenetic approach that captures the ...

Residual CFTR function in cystic fibrosis was associated with better glucose tolerance and insulin secretion, with CFTR ...

There are some genes that can promote cancer; they are sometimes called oncogenes, and in tumor cells, mutations are often found in these genes. When they are functioning normally, oncogenes are often ...

This important study introduces a new biology-informed strategy for deep learning models aiming to predict mutational effects in antibody sequences. It provides solid evidence that separating ...

A genetic mutation passed from mother to children in families affected by schizophrenia has now been shown to completely ...

A single microscopic change in our DNA can permanently alter how the brain is built, locking in developmental problems that no amount of later effort can fully undo. Researchers are now tracing how ...

Boston biotech Beam Therapeutics has announced initial data from a phase 1/2 trial of its gene therapy for a genetic lung and liver disease, with no serious adverse events reported among the nine ...