Figure 1: Ewing tumour cells with the EWSR1-FLI1 fusion are less sensitive to TGF-β. Figure 2: Regulation of the TGFBR2 promoter by EWS-FLI1 and FLI1, and electrophoretic mobility shift assay of in ...
In the 1990s, Lee Sweeney, a physiologist at the University of Pennsylvania, demonstrated that inserting the gene encoding insulin-like growth factor 1 (IGF-1) into the muscle cells of mice increased ...
A 'loopy' discovery in bacteria is raising fundamental questions about the makeup of our own genome -- and revealing a potential wellspring of material for new genetic therapies. A "loopy" discovery ...