MPN-BP transformation is driven by sequential mutations disrupting genomic stability, with TP53 mutations being strong predictors of progression. TP53 mutations confer a selective growth advantage, ...

For decades, geneticists have known that most common illnesses are not caused by a single rogue gene but by intricate constellations of DNA variants acting together in specific cells. Now a new ...

Researchers at the Francis Crick Institute and UCL have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through ...

Humans, who are classified among the five great apes, are closest genetically, i.e., DNA similarity, to chimpanzees (98.8%-99%) and bonobos (98.8%). [Blueringmedia ...

The contribution of genetics to the variability in people’s metabolism has remained largely unknown. This is, in part, because genetic studies of human metabolism have been limited in scale and ...

Modern humans descended from not one, but at least two ancestral populations that drifted apart and later reconnected, long before modern humans spread across the globe. Modern humans descended from ...

In tropical climates, lizards are everywhere. It can be a bit wild to see, and they come in all shapes and sizes. They seem a tad superfluous in such large varieties leaving one to wonder, what ...