Senescent fibroblasts are aging cells in connective tissue that no longer divide and protect against tumor development. Yet, these same cells can promote cancer growth in a laboratory setting. Until ...

A new study by the Garvan Institute of Medical Research has uncovered a hidden mechanism explaining why breast cancer can return many years after successful treatment. Published in Nature ...

Being overweight or obese has long been linked to a greater risk of developing or dying from breast cancer. New research suggests a reason: Certain breast cancer tumors may feed on neighboring fat ...

Cancer is caused by faulty genes, but what also shapes a cancer cell's behavior is how a gene's instructions are trimmed and rearranged before they are turned into the proteins that keep a cell alive.

Researchers have solved a long-standing mystery about why physical forces slow cancer growth—and the answer could reshape how ...

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Cancer always seems to break the rules — defying normal biology and finding new ways to survive, grow, and spread. That ability fascinated Rushika M. Perera, PhD, when she was younger. It’s what ...

Left: In normal gastric tissue, gastric epithelial cells rely on growth signals provided by the surrounding microenvironment. In particular, WNT signals — such as WNT2 secreted by neighboring cells — ...

Cancer cell DNA doubling — when cells accidentally duplicate all chromosomes without dividing — now has a new risk factor: ...

University of Virginia School of Medicine scientists have revealed how mistakes in the final step of cell division can have ...

A feature of pancreatic cancer cells’ surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

Published online Feb. 16 in the journal Cell, the new work shows that a main factor determining whether pancreatic cancer cells increase autophagy levels is their ability to detect the extracellular ...