Researchers comparing the human genome with the genomes of other species have discovered a surprising number of matching DNA sequences in a variety of vertebrate species, including the mouse, rat, dog ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

Genes contain instructions for making proteins, and a central dogma of biology is that this information flows from DNA to RNA to proteins. But only two percent of the human genome actually encodes ...

UMass Chan Medical School scientists have nearly tripled the known number of potential regulatory elements in the genome to 2 ...

Image Caption: Technologies evolved related to the Human Genome Project. Genes & Diseases publishes rigorously peer-reviewed and high quality original articles and authoritative reviews that focus on ...

In a keynote talk during GEN’s “The State of CRISPR & Genome Editing” virtual summit, originally broadcast on June 11, 2025, Neville Sanjana, PhD, Core Faculty Member at the New York Genome Center and ...

In a landmark effort to understand how the physical structure of our DNA influences human biology, Northwestern investigators and the 4D Nucleome Project have unveiled the most detailed maps to date ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

A new study challenges what's long been assumed about genetic variants thought to always cause inherited blindness.