For both research and therapeutic purposes, antibodies can be used to affect cellular processes in vivo and referred to as functional/in vivo grade antibodies. There are a wide range of applications ...

Fc engineering has many important uses in antibody drug development. It enhances antibody-dependent cellular cytotoxicity (ADCC) in the tumor microenvironment to increase tumor cell-killing efficacy ...

Antibody testing is likely to play an increasingly important role in the practice of rheumatology. The classification of lupus is enabled by antinuclear antibodies, as is rheumatoid arthritis (RA), by ...

CD40 receptor clustering driven by CD40 ligand or anti-CD40 antibody, 341G2 with the human IgG2 (h2) isotype. Jurkat cells expressing full length hCD40-green fluorescent protein (GFP), were treated ...