Trevor Lawrence took the Jacksonville Jaguars back to the playoffs with his nearly flawless work through the air.

49ers vs Colts final score, results: Brock Purdy throws five touchdowns, 49ers control destiny after win vs. Colts originally appeared on The Sporting News. Add The Sporting News as a Preferred Source by clicking here. The San Francisco 49ers have officially put their playoff destiny in their own hands.

The Indianapolis Colts lose their sixth straight game, while the Jacksonville Jaguars earn their seventh straight win.

You've seen the model's best bets for Jacksonville Jaguars vs. Indianapolis Colts. Now, get against the spread, total and money-line picks for every Week 17 NFL game here, all from the model that's simulated every game 10,000 times.

The Indianapolis Colts are in disarray after a sad finish to the season, and free agency looms with tough choices ahead.

Stay up to date here with the latest news and highlights from the Indianapolis Colts' Week 16 matchup on Monday Night Football against the San Francisco 49ers.

The Indianapolis Colts can't maintain their AFC South lead as the Houston Texans beat them: Results, live score updates, stats.

The Jacksonville Jaguars have already clinched a playoff berth. They now face the Indianapolis Colts eyeing improved seeding. Follow for live updates.

Monday Night Football closes out Week 16 with a huge matchup between the San Francisco 49ers and the Indianapolis Colts.

The Indianapolis Colts will bench Philip Rivers and start rookie quarterback Riley Leonard in Week 18, coach Shane Steichen announced Wednesday.

It might not seem like it from the 23-17 final score, but the Jacksonville Jaguars' defense shut down the Indianapolis Colts. 44-year-old quarterback Philip Riv