Despite the threat posed by antibiotic resistance in infectious bacteria, little is known about the diversity, distribution and origins of resistance genes, particularly among the as yet unculturable ...

The global proliferation of extended-spectrum β-lactamase (ESBL)-producing bacteria has escalated antimicrobial resistance, challenging treatment of common infections such as urinary tract infections, ...

Abbott Laboratories, AbbVie Inc., Alkem Laboratories Ltd., Astellas Pharma Inc., Cipla Inc., F. Hoffmann La Roche Ltd., GlaxoSmithKline Plc, Lupin Ltd., Meiji ...

Extended-spectrum β-lactamase-producing Enterobacterales (ESBL-E) have become a critical global public health challenge due to their high resistance to β-lactam antibiotics and association with severe ...

In the ongoing battle against antibiotic resistance, a new study published in Engineering by Zhuoren Ling’s research team unveils a promising triple combination of antibiotics that significantly ...

Let us consider the following hypothetical scenario. A 48-year-old man with a history of type 2 diabetes mellitus was recently on vacation in Calcutta, India. Three days into his stay, he was involved ...

Council of Scientific and Industrial Research (India) has synthesized substituted tricyclic heterocyclic compounds acting as β-lactamase IMP-1 (bacterial) and/or New Delhi metallo-β-lactamase-1 (NDM-1 ...

See related research article by Kus and colleagues on page 1257 and at www.cmaj.ca/lookup/doi/10.1503/cmaj.110477. From a diagnostic and microbiologic perspective ...

WHITEHOUSE STATION, N.J.--Merck (NYSE:MRK), known as MSD outside the United States and Canada, announced today that the U.S. Food and Drug Administration (FDA) has designated relebactam (previously ...

Tuojie Biotech (Shanghai) Co. Ltd. has disclosed boric acid derivatives acting as β-lactamase (bacterial) inhibitors reported to be useful for the treatment of bacterial infections.