IRSF investment positions organization at the forefront of early-stage Rett research as genomic medicine reshapes rare ...

MIT researchers have discovered that two common genetic mutations that cause Rett syndrome each set off a molecular chain of events that compromises the structural integrity of developing brain blood ...

MIT researchers have discovered that two common genetic mutations that cause Rett syndrome each set off a molecular chain of events that compromises the structural integrity of developing brain blood ...

Neuroscientists discover that Rett syndrome mutations cause a leaky brain via overexpressed miRNA-126-3p, pointing to a new therapeutic target for vascular repair.

Researchers at Baylor College of Medicine and the Jan and Dan Duncan Neurological Research Institute at Texas Children’s Hospital (NRI) have identified and characterized two regions of DNA required ...

Rett syndrome is a rare devastating neurological disorder that primarily affects young girls and manifests as an impaired ability to walk and talk, along with characteristic 'hand-wringing' movements, ...

This release is available in Spanish. A paper published online today in Molecular Cell proposes that Methyl CpG binding protein 2 (MeCP2) impacts the entire genome in neurons, rather than acting as a ...

Changes in the DNA methylation status are one of the most common molecular alterations in human neoplasia. Hypermethylation of CpG islands, especially when located in the promoter region, generally ...

A team of researchers has developed a strategy that allows them to identify potential treatments that would restore altered levels of MeCP2. Having twice the normal amount of the protein MeCP2, a ...

Only 300 people in the world have been diagnosed with a deadly genetic condition called MeCP2 duplication syndrome. MeCP2 duplication is a cureless neurological condition that typically affects males ...