This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

Food allergies affect more than half a billion people worldwide. In severe cases, even a small bite of the wrong food can trigger anaphylaxis - a rapid, body-wide allergic reaction that can cause ...

Researchers have created a nanotherapy that selectively targets and shuts down the immune cells responsible for causing an allergic response in mice, preventing anaphylaxis. Able to be tailored to ...

Q: My doctor thinks my mast cells are activating inappropriately and may be causing many of the symptoms I periodically have. Please tell me more about this condition. A: Mast cells are an important ...

– Data provide insights on the signaling pathways involved with AK006 mast cell inhibition –– AK006 has a distinct mechanism of action that leads to broad inhibitory effects on mast cells – The ...

Please provide your email address to receive an email when new articles are posted on . Barzolvolimab is an anti-KIT monoclonal antibody, and mast cells need KIT to survive. Weekly hive and itch ...

A prominent feature of CSU is its association with angioedema, observed in approximately 40% to 50% of patients with CSU; around 10% of patients primarily experience angioedema as the main symptom.

Scientists at Zhejiang University have found a way to turn allergy-causing cells in the body into cancer-fighting agents, offering a new targeted approach that combines immune system activation with ...