These immune CD8 T cells may provide a target for treating the buildup of fatty lesions in the arteries called atherosclerosis. Atherosclerosis is the underlying pathology of heart attacks and strokes ...

Virtual memory CD8+ T cells (T VM) are a relatively recent discovery in humans. A new review discusses what is known about them from mouse models and their cellular equivalents in humans, as described ...

Antigen-driven TCR signaling in the epidermis during CD8+ TRM differentiation results in a lower TGFβ requirement for persistence and increased proliferative capacity that together enhance epidermal ...

This study is led by Dr. Shuyang Yu (College of Biological Sciences, China Agricultural University), Dr. Jingyu Xu (The Collaborative Innovation Center of Tissue Damage Repair and Regeneration ...

A study has identified a metabolic switch in the immune system's T cells that is essential to the generation of memory T cells -- which confer lasting immunity to previously encountered pathogens -- ...

As the trained killers of the immune system, cytotoxic T cells silently save our lives every day—vanquishing viruses before they can run amok, and putting nascent cancer cells out of business before ...

Neuronal death is the indisputable endgame of Alzheimer’s disease, but what does the killing, and how? To try to solve the mystery, researchers have staged increasingly complex crime scenes in ...