ascopubs.org

Mismatch Repair system protein deficiency as a factor of resistance to chemo-radiotherapy treatment in patients with locally advanced rectal adenocarcinoma and its influence on ...

The significance of mucin on rectal MRI in patients with locally advanced rectal cancer being considered for watch-and-wait after neoadjuvant therapy. This is an ASCO Meeting Abstract from the 2023 ...
ascopubs.org

Association between deficient mismatch repair system and efficacy to irinotecan containing first-line chemotherapy in patients with sporadic metastatic colorectal cancer.

Selecting colorectal cancer (CRC) patients for therapy based on mutational analysis by next generation sequencing: Are we analyzing the appropriate tumor? Background: Colorectal cancer with deficient ...
Medicine Buffalo

Understanding the Mechanisms of DNA Mismatch Repair

This project has reached full capacity for the current term. Please check back next semester for updates. Errors in DNA replication occur at the replication fork, leading to misincorporation events, ...
Nature

Mismatch repair status may predict response to adjuvant chemotherapy in resectable pancreatic ductal adenocarcinoma

Deficiencies in DNA mismatch repair have been associated with inferior response to 5-FU in colorectal cancer. Pancreatic ductal adenocarcinoma is similarly treated with pyrimidine analogs, yet the ...