Seahawks minus 2 1/2 The winner earns the NFC's No. seed, a first-round bye and home-field advantage throughout the playoffs. The 49ers beat Seattle on the road in Week 1.

The final week of the 2025 NFL season is finally here! That means it's the last week for the SI Roundtable and it's everyone's final opportunity to build on the

Florio’s pick: 49ers 27, Seahawks 24. Simms’s pick: Seahawks 28, 49ers 24. A meaningless game will have plenty of meaning, if Tampa wins on Saturday. Florio’s pick: Saints 23, Falcons 20. Simms’s pick: Falcons 24, Saints 17.

Each pick has a confidence level of 1-10, with 10 being the most confident. For more information on the pick methodology, check out the Week 1 edition of this series. Keep in mind that since the idea here is to make high-percentage plays,

Matt Verderame makes his latest first- and second-team selections at each position, and the Broncos lead the way with five players.