Detailed mapping of CD4⁺ T cells from children with systemic lupus erythematosus (SLE) has revealed distinct immune cell subsets with likely roles in disease pathogenesis, according to a study led by ...
Immune-inflammatory skin diseases (e.g., psoriasis, atopic dermatitis) involve dysregulation of CD4+ T-cell subsets (Th1/Th2/Th17/Treg) and cytokine networks (IL-17/IL-23/IL-4). Biologics targeting ...
Hope for adults and children with cancers Camilla Jandus' team is currently preparing a clinical trial of TCR-engineered CD4-based cell therapy. The trial will include different types of cancer ...
The decrease in CD4 cells during HIV infection seems to be driven by immune activation, which does not always correlate with viral load. Experienced clinicians are all too familiar with the ...
Decades after its discovery, the emerging view of idiopathic CD4 lymphocytopenia (ICL) -- popularly dubbed "AIDS without HIV" -- is that it may be more homogeneous than originally thought, despite ...
*Adjusted model includes: age, sex, race/ethnicity, year of diagnosis, Deyo comorbidity index, smoking, alcohol abuse, time-dependent treatment, and organization. † Hazard ratios significant at a ...
Researchers have identified a novel type of immune cell, called the stem-like CD4 T cell, that plays a pivotal role in anti-tumor immunity. The pre-clinical findings highlight the potential to ...
Winship Cancer Institute of Emory University researcher Haydn T. Kissick, PhD, and assistant professor, Department of Urology at Emory University School of Medicine. Atlanta, GA — Oct. 23, 2024 — ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results
Feedback