Since the effects of gender-affirming therapy on fertility are unknown, multiple medical societies endorse the preservation of fertility in persons who identify as transgender. 1-3 In transgender male ...

In a new study published in the journal Nature, researchers in Japan report that activating just eight genes for producing gene-controlling proteins is enough to convert mouse stem cells directly into ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells, or oocytes, ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

The researchers were surprised to find a new, late function for Rnf212 in the oocyte selection process. The results are published Sept. 27 in the journal Molecular Cell. During oocyte quality control, ...

Memorial Sloan-Kettering Cancer Center program of cancer and aging. Experience of the 65+ Clinical Geriatric Program in the evaluation of older cancer patients ...

Oocyte cryopreservation is a suitable fertility preservation option for women who are not partnered, have ethical objections to cryopreserving embryos or wish to have complete reproductive autonomy.

With IVF and egg-freezing techniques, women no longer need to plan their family based on their biological clock. Hence, they get to focus on the other aspects of life, and then embrace motherhood when ...