Periportal assembloid, with the three component cell types visualized: cholangiocytes in pink, portal fibroblasts in green, and hepatocyte nuclei in blue; all cell borders are visualized in white. New ...

Assessing the toxicity of food contaminants—including carcinogenic potential—is a major challenge in evaluating the risks ...

The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...

Using human induced pluripotent stem cells, researchers have built a miniature 3D liver model that replicates the critical interaction between hepatocytes and stellate cells. As chronic liver disease ...

The paper S. Hoehme et al., “Prediction and validation of cell alignment along microvessels as order principle to restore tissue architecture in liver regeneration,” PNAS, 107:10371-76, 2010. Free ...

The model was trained and validated on more than 2,000 real-world cases from six U.S. transplant centers. The model accurately predicts the donor's time of death 75% of the time, outperforming both ...

The market is experiencing a significant transition from traditional 2D cell cultures to more sophisticated 3D liver models and liver-on-chip microfluidic systems. These new-generation systems better ...

VivoSim Labs' NAMkind™ platform shows 87.5% predictive accuracy for liver toxicity, enhancing drug safety and reducing development costs. VivoSim Labs, Inc. announced the successful performance of its ...

Discover how a miniature model of the human liver can help improve toxicology testing for food contaminants, reducing the need for animal testing.