Potassium channels can become nonconducting via inactivation at a gate inside the highly conserved selectivity filter (SF) region near the extracellular side of the membrane. In certain ligand-gated ...

This is a preview. Log in through your library . Abstract Since the availability of the first crystal structure of a bacterial Na⁺ channel in 2011, understanding selectivity across this family of ...

Potassium channels are essential membrane proteins that enable the selective and rapid transport of K⁺ ions, a process fundamental to cellular excitability and signal transduction. Recent research has ...

Tetrameric cation channels are the largest and best characterized group of ion channels. For this type of ion channel, the ion pathway lies in a pore domain consisting of two transmembrane helices ...

Despite being only a few nanometers in size, they are of fundamental importance for biological processes: Ion channels allow essential ions such as potassium and sodium to enter and leave our cells.