In ESR, a spin label is added to the target site using cysteine substitution. This is followed by modifying the sulfhydryl group with a paramagnetic nitroxide reagent. The ESR then provides ...

Site-direct spin labeling combined with electron paramagnetic resonance (EPR) spectroscopy is a powerful tool for detecting structural changes in proteins. This review provides examples that ...

Researchers develop a new site-directed spin labeling approach based on genetically encoded noncanonical amino acids amenable to Diels-Alder chemistry as well as a new spin label, PaNDA. Site-directed ...

Site-directed spin labelling (SDSL) used in combination with electron paramagnetic resonance (EPR) spectroscopy has been a tried and trusted technique for elucidating the structure, function and ...