Splicing of precursor mRNAs generally occurs co-transcriptionally, thus promoting the correct sequential splicing of exons as they emerge from RNA polymerase II. However, for alternatively spliced ...

Johns Hopkins researchers have developed a powerful new AI tool called Splam that can identify where splicing occurs in genes—an advance that could help scientists analyze genetic data with greater ...

This article was review by Thomas Cooper, MD from Baylor College of Medicine. Stay up to date on the latest science with Brush Up Summaries. Despite its significance, alternative splicing’s global ...

Fiber optic technology has reshaped the way data moves around the world. From undersea cables connecting continents to local ...

Important messages require accurate transmission. Big genes are especially challenging. During processing, introns (non-coding elements) are snipped out and exons (coding segments) pasted together to ...

As DNA is transcribed into RNA it needs to be edited to remove non-coding regions, or introns, shown in green. This editing process is called splicing, which involves removing the introns, leaving ...