Time to deterioration of physical function showed "meaningful superiority" over progression-free survival (PFS) as an early surrogate for overall survival in trials of immune checkpoint inhibitors ...
Suggested Citation: "Appendix B: Summary from the Committee's Report *Evaluation of Biomarkers and Surrogate Endpoints in Chronic Disease*." Institute of Medicine. 2011. Perspectives on Biomarker and ...
Minimal residual disease was “strongly” associated with overall survival at the patient level, researchers reported. Minimal residual disease (MRD) is “a credible intermediate endpoint” for some ...
FNIH Announces FDA Qualification of First Surrogate Endpoint for Use in Osteoporosis Clinical Trials
The MarketWatch News Department was not involved in the creation of this content. -- Measuring change in bone mineral density, rather than fracture occurrence, promises to speed development of new ...
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