Nature makes amide bonds—the key linkages that string together amino acids in a polypeptide—like a knitting whiz. The ribosome in Escherichia coli bacteria, for example, can make eight amide bonds in ...
Biologically active peptides have garnered considerable attention as drug candidates because their target specificity is generally higher than that of small molecule-based drugs, and their production ...
Solid-phase peptide synthesis is an indispensable method for constructing natural and modified peptide sequences. But the multistep process, even when automated, is extremely time-consuming for the ...
Manufacturing small proteins known as peptides is usually very time-consuming, which has slowed development of new peptide drugs for diseases such as cancer, diabetes, and bacterial infections. To ...
Peptides, as essential biomolecules linking amino acids and proteins, play a vital role across numerous disciplines, including life science research, drug discovery, biomaterials engineering, and ...
Vapourtec’s R-Series flow chemistry system, equipped with a UV-150 photochemical reactor, has been cited in research by scientists* at Novo Nordisk in the C-terminal α-amination of peptides and ...
Vapourtec’s Peptide-Builder, a fully automated, high-throughput benchtop peptide synthesiser, has been designed to redefine solid-phase peptide synthesis (SPPS). Compact, efficient and intuitive, it ...
Automation and advances in solid- and liquid-phase approaches are but a few factors driving costs down, according to this article from our July 1 issue. The continued strong demand for peptides as ...