Boosting KCC2 function reduced seizures and abnormal brain activity in temporal lobe epilepsy models. Learn how this strategy could aid drug-resistant epilepsy.

Many patients suffer from epilepsy that cannot be controlled by current medications. Surgical removal of epileptogenic brain regions is effective in only about half of cases, and not all patients are ...

Researchers identify prochlorperazine as a potential new treatment for temporal lobe epilepsy by restoring the KCC2 chloride ...

Epilepsy affects approximately 1-in-26 people and the most common form, known as temporal lobe epilepsy (TLE), often cannot be adequately treated with anti-seizure medications. Patients with this form ...

Seizures can be predicted more than 30 minutes before onset in patients with temporal lobe epilepsy, opening the door to a therapy using electrodes that could be activated to prevent seizures from ...

In a retrospective cohort, a clinical heuristic composed of eight binary variables helped identify which patients with medial temporal lobe epilepsy (MTLE) were best suited for stereotactic laser ...

Please provide your email address to receive an email when new articles are posted on . Retrospective chart review included 29 patients with drug-resistant epilepsy who underwent LITT. Better 1-year ...

Please provide your email address to receive an email when new articles are posted on . Surgery for mesial temporal lobe epilepsy correlated with a reduction in imaging-defined brain age, indicating ...

Scientists have developed a new therapeutic concept for the treatment of temporal lobe epilepsy. It represents a gene therapy capable of suppressing seizures at their site of origin on demand. Having ...