THE coumarin anticoagulants depress the synthesis of four clotting factors: prothrombin; proconvertin (factor VII); Stuart factor (factor X); and plasma thromboplastin component, or PTC (factor IX).
IN 1944 indandione derivatives were reported by Kabat, Stohlman and Smith 1 to be capable of producing hypoprothrombinemia in laboratory animals. These workers studied several compounds with different ...
A prothrombin time (PT) test measures the amount of time it takes for your blood plasma to clot. Prothrombin, also known as factor II, is just one of many plasma proteins involved in the clotting ...
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