The human body is composed of over 37 trillion cells, each with a limited lifespan. These cells are continuously replaced to maintain organ and system function. Yet over time, or as a result of damage ...

The cartilage extracellular matrix (ECM) primarily consists of glycosaminoglycans (GAGs) and proteoglycans (PGs), which contribute to the tissue’s biomechanical properties by forming a slippery ...

Mesenchymal stem cell-derived extracellular matrix (mECM) is increasingly recognized in tissue regeneration due to its high biocompatibility, controllability, and customizability. In musculoskeletal ...

For centuries, the inability to regrow lost body parts has been considered a defining limitation of humans and other mammals. While animals like salamanders can regenerate entire limbs, humans are ...

Glucose is life's main energy source. But a new study reveals a surprising role as a master manipulator of tissue maturation, hinting at its importance in diabetes and cancer. The sugar glucose, which ...