This short chapter summarizes some of the key discussions concerning how drug abuse is viewed in the society and the implications of those views. These discussions occurred throughout the committee's ...

Overexpression of Shisa7 in the orbitofrontal cortex in drug-free rats induced comparable up and down changes in gene expression as that induced by the self-administration of heroin. The concordant ...

Consider two adult siblings who grew up in the same household and same family atmosphere. One sibling can drink socially—he enjoys a beer now and then, but overall, he can take it or leave it—while ...

Addiction science is at an impasse. Rates of addiction remain high. Translational results from decades of research conducted within the dominant brain disease paradigm are shockingly meager. Meanwhile ...

The opioid epidemic is arguably the most devastating public health crisis of our time. Americans are acutely aware of the crisis’ general devastation, yet the humanity of the crisis often fades behind ...

Opioid use disorder is associated with more than 350,000 deaths annually worldwide. Guided by the need for an increased understanding of critical neurobiological features of addiction, researchers ...

Substance use disorders continue to affect individuals, families, and communities across the United States. In Indiana ...

The Camden County Board of Commissioners and the Addiction Awareness Task Force (AATF) launched the Break the Stigma campaign to change the conversation around addiction and recovery. This initiative ...

In a recent New York Times essay, Patti Davis, daughter of former president Ronald Reagan, reflects on the destructive power of addiction in her life. She describes waiting with others to snort ...

Researchers have found a unique molecular signature and genes in the orbitofrontal cortex associated with heroin-seeking behavior. A preclinical rodent model implicated a gene called Shisa7 as the key ...