Gene expression analysis and RNA sequencing have transformed our understanding of molecular biology, offering a comprehensive view of transcriptomic landscapes in diverse biological systems. By ...

More than 60 years after its discovery, scientists are still learning surprising ways DNA stores and translates instructions ...

Human genes are written in long strings of three-letter units composed of four different nucleotides. These units—or ...

Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...

Lipid nanoparticles, or LNPs, are best known as the delivery vehicle for the COVID-19 mRNA vaccines received by billions of people. But they are now at the center of a much larger medical revolution, ...

A new class of lipids improve the rates at which lipid nanoparticles (LNPs) successfully deliver RNA therapeutics and gene editing tools, promising to increase their effectiveness of such treatments.

Platform combines proprietary AI sequence optimization, novel genetic parts, and lab validation in application-relevant cell models to improve expression and half-life, delivering top candidates in ...

Researchers have developed a new lipid nanoparticle design that directs mRNA to the pancreas by exploiting the organ’s own ...

Researchers demonstrate that a circular RNA-based AAV platform significantly enhances gene expression in vivo compared with conventional mRNA approaches.

Preliminary Phase 1 Study Results Show Strong Anti-Tumor Activity and Favorable Safety Profile for First-in-Class Small Molecule MYB mRNA ...

Lipid nanoparticles, or LNPs, best known as the delivery vehicle for the COVID-19 mRNA vaccines received by billions of people, are now at the center of a much larger medical revolution. Researchers ...