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  1. What Is Histamine? - Cleveland Clinic

    Mar 28, 2023 · Histamine is a signaling chemical your immune system releases to send messages between different cells. Histamine has several functions, but it’s mainly known for its role in causing …

  2. Histamine - Wikipedia

    Histamine, a biogenic amine, involves many physiological functions, including the immune response, gastric acid secretion, and neuromodulation. However, its rapid metabolism makes it challenging to …

  3. What Is Histamine and What Is Its Role in the Body? - Healthline

    Oct 2, 2023 · Histamine is a chemical that your body produces, playing a vital role in immune responses, particularly those related to allergies, and also influencing the gut, brain, and overall immune...

  4. Histamines: What they do, and how they can overreact - WebMD

    Aug 14, 2022 · WebMD explains histamines, a defense mechanism your body employs to fight off allergens.

  5. Histamine: Function, Reactions and Side Effects - Medicover Hospitals

    Oct 4, 2024 · Histamine acts as a neurotransmitter, facilitating communication between nerve cells in the brain. It is involved in regulating sleep-wake cycles, appetite, and cognitive functions.

  6. Histamine | Description & Facts | Britannica

    Dec 13, 2025 · Histamine works by binding to histamine receptors on the surface of cells. There are four kinds of receptors, called H 1, H 2, H 3, and H 4. The activity of histamine can be blocked by various …

  7. The Role of Histamine as a Neurotransmitter - ScienceInsights

    Nov 15, 2025 · In the central nervous system (CNS), histamine functions as a neurotransmitter, regulating numerous physiological processes. The brain’s histaminergic system is a small but …

  8. Histamine: Functions, Effects, and Role in Your Body

    Oct 19, 2025 · Discover histamine's vital role in your body - from allergic reactions to sleep regulation, digestion, and cognitive function. Learn how this important chemical affects your health.

  9. Histamine Neurotransmitter: What Is Its Role in the Brain?

    Aug 3, 2025 · Histamine functions as one such neurotransmitter within the central nervous system, influencing a wide array of physiological and cognitive processes. Understanding histamine’s actions …

  10. Biochemistry of Histamine: Functions and Significance in ... - DoveMed

    Aug 25, 2023 · Histamine is a biogenic amine that plays diverse roles in various physiological processes. It functions as a neurotransmitter, immune modulator, and regulator of gastric acid …