MCP-1: Function, regulation, and involvement in disease - PMC
MCP-1 (Monocyte chemoattractant protein-1), also known as Chemokine (CC-motif) ligand 2 (CCL2), is from family of CC chemokines. It has a vital role in the process of inflammation, where it attracts or …
CCL2 - Wikipedia
"RANTES and monocyte chemoattractant protein-1 (MCP-1) play an important role in the inflammatory phase of crescentic nephritis, but only MCP-1 is involved in crescent formation and interstitial fibrosis".
Role of MCP-1 as an inflammatory biomarker in nephropathy
Jan 4, 2024 · Abstract The Monocyte chemoattractant protein-1 (MCP-1), also referred to as chemokine ligand 2 (CCL2), belongs to the extensive chemokine family and serves as a crucial mediator of …
MCP 1 in Immune Regulation: Inflammatory Role & Chronic Diseases
Apr 29, 2025 · Monocyte chemoattractant protein-1 (MCP-1) plays a key role in immune regulation by directing monocytes and other immune cells to sites of inflammation. While essential for normal …
What Is MCP-1 and Its Role in Chronic Disease? - ScienceInsights
MCP-1 plays a significant role in the body’s immune response by coordinating the movement of specific white blood cells to sites of injury or infection. Establishing its function in both health and disease is …
MCP-1 Definition - Anatomy and Physiology I Key Term | Fiveable
MCP-1, or Monocyte Chemoattractant Protein-1, is a chemokine that plays a crucial role in the innate immune response by recruiting and activating monocytes and macrophages to sites of inflammation …
Urinary MCP-1: Key Biomarker for Kidney Inflammation Detection
The urinary monocyte chemoattractant protein-1 (MCP-1) test is a non-invasive diagnostic tool used to measure MCP-1 levels in urine. This test plays a crucial role in assessing kidney inflammation and …
Renal monocyte chemoattractant protein-1: an emerging universal ...
May 14, 2019 · Monocyte chemoattractant protein-1 (MCP-1) (also known as CCL2) is a member of a large family of chemotactic cytokines (chemokines) known to be important soluble mediators of …
MCP-1: Its Function in Inflammation and Disease
Aug 2, 2025 · MCP-1’s primary function is to attract monocytes, a type of white blood cell, to areas of infection or injury. It does this by acting as a chemotactic factor, creating a chemical gradient that …
The chemokine MCP-1 (CCL2) in the host interaction with cancer
Jan 29, 2018 · MCP-1 is a potent monocyte-attracting chemokine, identical to the previously described lymphocyte-derived chemotactic factor or tumor-derived chemotactic factor, and greatly contributes …